Respected sir, I have completed my Ph.D. work in H.E.J. research institute of chemistry, Karachi, Pakistan (with Prof. Dr. Abdul Malik) and University of Southampton, United Kingdom (with Prof. Dr. Jeremy D. Kilburn) I worked on the Isolation and structure elucidation of bioactive natural products from the important medicinal plants (H.E.J, Karachi, Pakistan) and Supramolecular chemistry (University of Southampton, U.K.). During my doctoral work I have isolated several interesting natural products out of which nine were new and also displayed excellent biological activities and I have synthesize a novel macrocycle. In research, I proved myself to be productive and have published some good papers in International journals. I am well-versed and quite experienced in the use of classical and modern instruments. I am able to independently establish the chemical structure of compounds using highly sophisticated spectroscopic techniques. Moreover I can express very well verbally and in writing in the English language. I have successfully passed the courses mentioned in enclosed C.V. in which I secured very good grades. I have a very keen and objective approach, which will help me in my theoretical as well as in research fields. I want to get this position. I will prove myself as a hard worker and good chemist.
Thanks
Shagufta Perveen
H. E. J. Research Institute of Chemistry,
International Centre for Chemical and Biological Sciences,
Lab 322, c/o Prof. Dr. Abdul Malik
University of Karachi , Karachi 75270 , Pakistan .
Cell # 0300-7061188
Tel. Office: (+92)-21-4824924-5; Ext. 208
Fax: (+92)-21-4819018-9, E-mail: shagufta_iccs@yahoo.com
Objective:
A challenging position in research in Chemistry utilizing my 5-years of research experience in international labs of HEJ ICCBS, Karachi, Pakistan (with Prof. Dr. Abdul Malik) & University of Southampton, Southampton, SO17 1BJ, United Kingdom (with Prof. Dr. Jeremy D. Kilburn, Dean Faculty of science) working with modern techniques of isolation and synthesis.
PERSONAL DETAILS
Date of Birth: 14 April 1979
N.I.C. #: 42201-0383909-0
Languages: English, Urdu
Marital Status: Single
Nationality: Pakistani
Sex: Female
Passport #: AP3999091
SCHOLARSHIPS
Research Fellowship from H.E.J. (ICCBS) (2003-2004).
Indigenous PhD Scholarship. Higher Education Commission, Govt. of Pakistan (after passing GRE Test General, NTS, National Base).
Initiative research scholarship for abroad Higher Education Commission Pakistan, Govt. of Pakistan.(after passing GRE Test Subjective, ETS, (Chemistry) International Base)
Research during M.phil/ Ph.D
HEJ ICCBS, Karachi , Pakistan
1-Isolation of Natural products from biologically active plants
"Chemistry of Labiatea Plant Perovskia atriplicifolia."
"Chemistry of Boraginaceae Plant Heliotropium subulatum."
"Chemistry of Asclepiadaceae Plant Vincetoxicum stoskii "
2-Supramolecular Chemistry
University of Southampton, U.K.
"Synthesis of Switchable N-pyridyl-thiourea/ urea based macrocycles"
Research Publications
1. Phenolic constituents from Perovskia atriplicifolia S. Perveen, A. Malik, Nat. Pro. Res.
(2006), 1.
2. Butyrylcholinesterase inhibitory guaianolides from Amberboa ramosa, S. Perveen, A. Malik, Arch Pharm Res. 28, 172-176 (2005).
3. Phytochemical studies of Amberboa ramosa, A. Malik, S. Perveen, Chemical Society of
Pakistan (2005).
4. A new flavonol glycoside from Amberboa ramosa, , A. Malik, S.Perveen, Nat. Pro.
Res. (2006), 20, 335.
5. Phytochemical studies of Perovskia atriplicifolia, S. Perveen , A. Malik, Chemical
Society of Pakistan (submitted).
6. Phytochemical studies of Heliotropium subolatum, S. Perveen , A. Malik Chemical
Society of Pakistan (2005), 27, 538.
7. Atripliside A & B, Two New Glycosides from Perovskia atriplicifolia, S. Perveen, A.
Malik, Z. naturforsch, 863, (2007), 62b.
8. Pervosides A and B, New Isoferulyl Glucosides from Perovskia atriplicifolia, S.
Perveen, A. Malik, J.A.N.P., (2007), (in press).
9. Terpenoidal constituents from Perovskia atriplicifolia, J.A.N.P., (2008), (submitted).
Advanced course work:
• Four complete courses in Advance Organic Chemistry
Physical methods
Structure and reactivity
Synthesis-1
Synthesis-2
• Advance course in X-Ray crystallography
• Advance course of synthesis by Dr. Richard C. D. Brown in University of Southampton .
• Attended training courses in HPLC, IR, UV, CD, 1D- and 2D-NMR techniques.
• Certificate course “An Introduction to Bioinorganic & Medicinal Chemistry of Metals”.
• A certified course of advanced organic synthesis conducted with Prof. Ichia Ninomiya at ICCBS, Karachi University .
International Conferences/Workshops Attended, Posters
1- 3rd international and 13th National chemistry conference under the auspices
of chemical society of Pakistan , Dec 28-31 2003.
2. 4th International Symposium on Natural Product Chemistry, January 10-13, 2004, Karachi , Pakistan .
3. 9th International Symposium on Natural Product Chemistry January 14-16,
HEJ Research Institute of Chemistry, University of Karachi , Karachi , Pakistan
4- Pak-Japan chemistry conference on Lashminiases Jan. 17-19, 2004
5- Pak-France symposium on natural product chemistry, Jan. 2004.
6- 4th International & 14th National Chemistry Conference under the auspices of
Chemical Society of Pakistan .
7. 5th International and 15th National Chemistry Conference, November 24-27, 2005, Islamabad , Pakistan .
8. International conference on synthetic chemistry, University of Reading, U.K.
9. International conference on Supramolecular chemistry, University of Southampton, U.K.
10. International conference on synthetic chemistry, University of Bristol, U.K.
11. National conference on Organic chemistry, University of Punjab, Lahore
Pakistan, 25-27 Feb, 2008.
And other several seminars by the expertise of the field from Pakistan and others
countries with several valuable topics and technology which link to organic
synthesis, isolation of natural products and their medicinal importance.
Seminars:
H.E.J. Research Institute of Chemistry
University of Karachi, Pakistan
2005
Delivered a seminar on "The total Synthesis of Epicylindrospermopsin".
H.E.J. Research Institute of Chemistry
University of Karachi, Pakistan 2007
Delivered a seminar on "Enantioselective Synthesis of Apoptolidinone".
H.E.J. Research Institute of Chemistry University of Karachi , Pakistan 25-01-2008
Delivered a work seminar on "Pyhtochemical investigations on the chemical constituents of Perovskia atriplicifolia & Supramolecular chemistry”
Delivered a seminar on "The total Synthesis of Epicylindrospermopsin".
University of Punjab, Lahore , Pakistan 26-04-08, 2008
• 4 years research experience as Ph.D Scholar at HEJ research Institute of Chemistry , University of Karachi , Pakistan .
• 8 months experience as Ph.D Scholar at University of Southampton , SO17 1BJ
U.K.
• Present Position: Ph.D. Research Fellow (Thesis submitted To HEJ committee) with Professor Dr. Abdul Malik, at International Centre For Chemical & Biological Sciences, H.E.J. Research Institute Of Chemistry, University of Karachi, Karachi-75270, Pakistan.
Educational Qualifications:
Degree University/ Board Year of Passing Subject
GRE International (ETS) 2005 Chemistry
GRE National (NTS) 2004 General
Ph.D. (ICCBS) H.E.J. 2008 Organic Chemistry
(Thesis submitted)
To HEJ committee
M.phil (ICCBS) H.E.J. 2005 Organic Chemistry
M. Sc. Fed. Govt. Urdu
Sci. college 2001 Organic Chemistry
B. Sc. Fed. Govt.Urdu
Sci. College 1998 Chem. Biology
.
F.Sc. Board of Sec. edu. 1996 Chem. Phy. Bio.
S.Sc. Board of Sec. edu. 1994 Chem. Phy. Math. Bio.
Special Courses
• Practical Synthetic Course. We performed multi step synthesis, a number of name reactions, stereo selective Photochemical and thermodynamically controlled reactions also performed even sensitive reaction and stereo selective photochemical reductive cyclization type reactions. I have performed a number of name reactions for the derivatization of Novel natural products and synthesis of small molecules.
• X-rays crystallography Prof. Dr. Masud Parvez ( Calgary University Canada ).
• Certificate for attended a lecture entitled “Biochemical basis of Diabetes and Ageing”15-24 April 2003 organized by HEJ, conducted by Dr. Nesar Ahmed Dept of Biological science, Manchester Metropolition Universitiy, U. k
• A certificated is awarded for the successful completion of the course entitled “An isolation to Bioinorganic and Medicinal chemistry of Metal “ held on 17 May 2003 at HEJ conducted by Dr. Mohammad Mahroof Tahir Assistant Professor St. Cloud State University Minneola, USA.
• A certificate course of basic Mathematics.
• Course and training of firefighting and Safety Management
Skills:
• Work well in chemical laboratory settings.
• Communicate efficiently and able to teach others.
• Working knowledge of PCs.
• Working knowledge of Windows 95/98/2000/XP operating systems
• Work well with various instruments used in lab, testing and research.
NMR (1D & 2D 1HNMR, Bruker)
Mass (EI/FAB/HR/ESI etc.)
UV/IR
HPLC (Recycling preparative LC-908 JAI Japan, Analytical LC-6A Shimadzu)
• Extensive use of Chem Draw, Chem Draw Suite, 1H-NMR & 13C-NMR software, Corel Draw, PowerPoint, ISIS Draw, Excel, Lotus, Word, WordPerfect.
• Extensive experience of working with literature search data base i.e. Science finder, and ISI web of knowledge.
RESEARCH INTERESTS
a) Isolation and structure elucidation of bioactive compounds from natural sources.
b) Asymmetric synthesis, superamolecular chemistry, Strategies and tactics for
free radical carbocyclization and transition metal mediated.
c) Synthesis and SAR studies of bioactive compounds.
d) Industrial analysis and problem solving.
References:
1- Prof. Dr. Abdul Malik Professor at H.E.J. Research Institute of Chemistry University of Karachi, Karachi-75270, Pakistan, E-mail: abdul.malik@iccs.edu & hejric@digicom.net.pk.
2- Dr. M. Shaiq Ali, Assistant Professor at H.E.J. Research Institute of Chemistry University of Karachi, Karachi-75270, Pakistan. e.mail: Shaiq303@super.net.pk & hejric@digicom.net.pk.
3- Prof. Dr. J. D. Kilburn, Dean Faculty of science at university of Southampton , Southampton , U.K. e.mail: jdk1@soton.ac.uk
